|
KMID : 0363019740040010017
|
|
Journal of Korean Academy of Periodontology
1974 Volume.4 No. 1 p.17 ~ p.24
|
|
|
Effects of Diphenylhydantoin on Salivary Gland and Liver Tissue In Experimental Dogs
|
|
Moon Dong-Sun
Lee Jae-Hyun
Kim Jong-Eun
|
|
|
Abstract
|
|
|
|
The purpose of the present experiment is to clarify the effects of the diphenylhydantoin on salivary gland and liver tissue. Twelve young adult dogs of about -6 mouth old with permanent dentition were used as experimental animals. Those animals divided into four groups; Group I Control group; Group II. Local irritatiofl group; Group III Dilantin administered plus local irritation; acid Group IV Dilantin admrini= stered group. Dilantin was given orally with daily dosage of 7 mg per kilo$reh of the body weight. Those animals were sacrificed at intervals of 37,44, and 50 days and fixed in 10% neutro-formalin solution. The tissue was ´prepared in serial section and staining process was made with Hematoxylin-eosin, Vangieson, R. N. A., and P. A. S. staining. The results obtained are summarized as follows; 1. The histologic features of salivary gland and liver tissue showed no difference between the control and the local irritation group. 2. Severe inflammatory changes were
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|